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Advising InSilico Medicine on milestone HKEX IPO listing, driving growth in AI and biotechnology

Dec 30, 2025

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We advised InSilico Medicine Cayman TopCo ("InSilico Medicine"), a reputable AI-driven biotechnology company with global operations, on its successful IPO on the Main Board of the Hong Kong Stock Exchange ("HKEX"), backed by 15 cornerstone investors including Eli Lilly, Tencent and Temasek.

The Walkers team, led by partners Andrew Barker and Mark Cummings, and supported by senior associates Beverly Lui and Flora Lo, and associate Samantha Currie, advised on all the Cayman Islands legal aspect of the transaction. We worked closely with InSilico Medicine's lead counsel Davis Polk & Wardwell to ensure seamless execution across multiple jurisdictions.

Accelerating innovation and industry development

This listing underscores the development trends in emerging sectors such as AI and biotechnology. It enables InSilico Medicine to advance its clinical pipeline through its proprietary Pharm.ai platform and to invest further in cutting-edge technologies, including generative AI and automated laboratories. InSilico Medicine raised HK$2.277 billion in this IPO, achieving the largest biotech IPO in Hong Kong this year, as in the size of fundraising.

Guiding clients through complex, multi-jurisdictional transactions

Andrew Barker commented, "We are proud to have provided ongoing support to InSilico Medicine, particularly in helping it reach this milestone transaction. It highlights investor confidence in emerging sectors and demonstrates our ability to deliver strategic, multi-jurisdictional legal solutions that empower clients to scale globally."

Mark Cummings added, "Our cross-border Corporate team thrives on guiding clients through complex corporate transactions. This successful listing reinforces Walkers’ commitment to delivering innovative, round-the-clock legal advice that helps businesses navigate uncharted waters and seize opportunities in dynamic markets."

Congratulations to everyone involved in this transaction.

 
Corporate, Mergers & AcquisitionsCayman IslandsHong Kong

MEDIA CONTACT

Shana Ray

Head of Business Development - Asia and Middle East

T/+852 2596 3302
M/+852 9030 6084
E/Email Shana Ray

KEY CONTACTS

Get in touch with our team

Andrew Barker
Andrew Barker

Andrew Barker

Partner

Cayman Islands

T

+1 345 914 4282

M

+1 345 525 2696

E

Email Andrew Barker
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Mark Cummings
Mark Cummings

Mark Cummings

Partner

Hong Kong

T

+852 2596 3316

M

+852 9189 6305

E

Email Mark Cummings
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Beverly Lui
Beverly Lui

Beverly Lui

Senior Associate

Hong Kong

T

+852 2596 3430

M

+852 6010 3031

E

Email Beverly Lui
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Flora Lo
Flora Lo

Flora Lo

Senior Associate

Hong Kong

T

+852 2596 3469

M

+852 9225 7817

E

Email Flora Lo
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Samantha Currie
Sam Currie

Samantha Currie

Associate

Cayman Islands

T

+1 345 914 4277

E

Email Samantha Currie
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